Effects of postconditioning with N,N,N'N'-tetrakis-2-pyridylmethyl-ethylenediamine in isolated rat hearts / 대한마취과학회지

BACKGROUND: It was reported that N,N,N'N'-tetrakis-[2-pyridylmethyl]-ethylenediamine (TPEN), a transition metal chelator, confers cardioprotection against myocardial ischemic injury. In this study, we investigated the effect of TPEN targeting reperfusion period in isolated rat hearts. METHODS: Langendorff perfused rat hearts were subjected to 30 min of regional ischemia and 2 h of reperfusion. Hearts were randomly assigned to either control (n = 9) or 10 micrometer of TPEN (n = 8) groups. TPEN was perfused for a period of 5 min before and 30 min after reperfusion. RESULTS: The ratio of infarct area/ischemic area (AN/AR) was significantly reduced in TPEN treated hearts (6.9 +/- 1.7%, P 0.05). CONCLUSIONS: Pharmacological postconditioning with TPEN reduces myocardial infarction however, TPEN does not modify post-ischemic systolic dysfunction in isolated rat hearts.

A Case of Aplastic Anemia in 2 Consecutive Pregnancies / 대한산부인과학회잡지

Aplastic anemia in pregnancy is an extremely rare condition with high maternal morbidity and mortality rates. Prognosis is poorer when aplastic anemia is complicated during pregnancy and many such patients have an unsuccessful pregnancy outcome. The relationship between aplastic anemia and pregnancy remains uncertain. Intensive hematological support remains the mainstay of therapy and a successful obstetric outcome can be best accomplished with the close clinical collaboration of the hematologist and the obstetrician. We report here a case of a 24-year-old woman with aplastic anemia, she experienced two consecutive vaginal deliveries. We present it with brief review of literature.

Prenatal diagnosis of a Subamniotic Hematoma / 대한산부인과학회잡지

Subamniotic hematoms are rare placental pathological lesions resulting from the rupture of chorionic vessels near the cord insertion. Most subamniotic hematomas are found after birth and result from excessive traction on the umbilical cord at delivery. The development of these lesions has been rarely reported in utero. A case of a subamniotic hematoma was diagnosed by ultrasound at 7(+5) weeks of gestation. We describe the ultrasound features of a subamniotic hematoma and the differential diagnosis.

A Study of Sailor Psychiatric Inpatients: Focusing on the Transition in a General Hospital / 신경정신의학

OBJECTIVES: The object of this study was to help the clinicians understand the characteristics of the sailors who were admitted to the psychiatric ward through elucidating the transition in the psychiatric aspect of them. METHODS: The results obtained from psychiatric records of 98 sailors who were admitted to department of psychiatry in a general hospital, from March 1, 1985 to Feb. 28, 1994 were compared with the results obtained from 34 sailor inpatients in the same hospital from March 1, 1982 to Feb. 28, 1985. RESULTS: 1) The number of sailor inpatients showed declining tendency and the age of them showed increasing tendency. 2) The number of patients of somatoform disorder, posttraumatic stress disorder, and organic mental disorder was increased. The number of patients of schizophrenia and mood disorder was decreased. 3) The proportion of inpatients from overseas fishing ship was increased markedly. We must ave a countplan and careful consideration f3r them. 4) We could infer that the groups of low education, crew, overseas fishing ship and below S year of employment duration had high admitted patient occurrence rate. The proportion of psychosis in the groups that were primitive school graduated and 1-5 year of employment duration was high relatively to neurosis(statistically not significant). 5) According to psychological test, the majority of sailor inpatients had constricted thought content, emphasis of responsibility for the family, submissive attitude to an authoritive figure and paranoid tendency. The MMFI profile of neurotic patients showed the tendency of finking bad.